Both banks are major banks in the US, which offers a wide range of banking services.
Chase bank is known for its easy-to-use mobile apps, digital banking services, large-scale ATM networks, and good reward system.
Wells Fargo is famous for their extensive branch network, wide range of financial products, and excellent customer service.
You can choose Chase Bank if digital experience is your priority. However, Wells Bank offers excellent in-branch support. The bank you will choose will depend on your priorities and needs.